| Объем | 100 мкл |
| Синонимы | PTN11, PTP-1D, PTP-2C, PTP2C, PTPN11 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q06124 |
| Иммуноген | Peptide sequence around phosphorylation site of tyrosine 542 (H-E-Y(p)-T-N) derived from Human SHP-2. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 |
| Примечание | <p>Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. <br /><br />Ferjoux G, et al. (2003) Mol Biol Cell. 2003, 14(9): 3911-3928. <br />Shi ZQ, et al. (2000) Mol Cell Biol. 20(5): 1526-1536. <br />Li C, Friedman JM. (1999) Proc Natl Acad Sci U S A , 96(17): 9677-9682 <br />Manes S, et al. (1999) Mol Cell Biol. 19(4): 3125-3135. <br />Oh ES, et al. (1999) Mol Cell Biol, 19(4): 3205-3215. <br /> ,</p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Tyr542 |
| Области исследований | Neuroscience,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells untreated or treated with starvation using SHP-2(Phospho-Tyr542) Antibody.
 |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SHP-2(Phospho-Tyr542) Antibody(left) or the same antibody preincubated with blocking peptide(right).
 |
| | |
Наименование: Phospho-PTPN11 (Tyr542) Antibody.