| Объем | 100 мкл |
| Синонимы | 70Z-SHP, HCP, HCPH, Hematopoietic cell protein-tyrosine phosphatase, PTN6 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P29350 |
| Иммуноген | Peptide sequence around phosphorylation site of tyrosine 536 (S-E-Y(p)-G-N) derived from Human SHP-1. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, IHC, IF,IHC:1:50-1:100, IF:1:100-1:200 |
| Примечание | Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus.<br/><br/>Migone TS, et al. (1998) Proc Natl Acad Sci USA, 95(7): 3845-3850.<br/>Timms JF, et al.(1998) Mol Cell Biol, 18(7): 3838-3850.<br/>Kanagasundaram V, et al. (1999) Mol Cell Biol, 19(6): 4079-4092.<br/>Hauck CR, et al. (1999) Infect Immun, 67(10): 5490-5494.<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Tyr536 |
| Области исследований | Cancer,Cell biology,Developmental biology,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SHP-1(Phospho-Tyr536) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Immunofluorescence staining of methanol-fixed Hela cells using SHP-1(Phospho-Tyr536) Antibody.
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Наименование: Phospho-PTPN6 (Tyr536) Antibody.