Phospho-BMX (Tyr566) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | BMX, BMX NON-receptor tyrosine kinase, Bone marrow kinase BMX, Epithelial and endothelial tyrosine kinase, NTK38 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P51813 | | Иммуноген | Peptide sequence around phosphorylation site of Tyrosine566 (D-Q-Y(p)-V-S) derived from Human ETK. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | <p>Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival, cell adhesion, and apoptosis. Participates in signal transduction stimulated by growth factor receptors, cytokine receptors, G-protein coupled receptors, antigen receptors and integrins. Induces tyrosine phosphorylation of BCAR1 in response to integrin regulation. Activation of BMX by integrins is mediated by PTK2/FAK1, a key mediator of integrin signaling events leading to the regulation of actin cytoskeleton and cell motility.<br/><br/>Zhang R, et al. (2003) J Biol Chem 278, 51267-76 <br />Tsai YT, et al. (2000) Mol Cell Biol 20, 2043-54 </p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | | Абревеатура | Phospho-Tyr566 | | Области исследований | Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HeLa cells treated with Serum using Phospho-ETK (Tyr566) antibody.The lane on the right is treated with the antigen-specific peptide.
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Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкл | | Кат. номер: | CSB-PA993762 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Phospho-BMX (Tyr566) Antibody.
Примечание: дополнительная информация (на английском языке). |
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