Объем | 100 мкл |
Синонимы | IER3, NFBD1, KIAA0170, DKFZp781A0122, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q14676 |
Иммуноген | Peptide sequence around phosphorylation site of Serine 513(E-R-S(p)-Q-A) derived from Human MDC1. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, IHC,IHC:1:50-1:100 |
Примечание | <p>The MDC1 protein contains a forkhead homology-associated (FHA) domain and 2 BRCA1 (MIM 113705) C-terminal motifs (BRCTs) and is required for the intra-S-phase DNA damage checkpoint.<br/><br/>Nagase T., DNA Res. 3:17-24(1996).<br />Shiina T., Genetics 173:1555-1570(2006).<br />Mungall A.J., Nature 425:805-811(2003).<br /></p> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Абревеатура | Phospho-Ser513 |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemical analysis of paraffin-embedded human brain tissue using MDC1 (Phospho-Ser513) antibody (left)or the same antibody preincubated with blocking peptide (right).
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