| Объем | 50 мкл |
| Синонимы | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q92569 |
| Иммуноген | Synthetic peptide of human PIK3R3 |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
| Примечание | Phosphatidylinositol 3-kinase is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol and related compounds at the 3’ position. PI 3-kinase p55 (PIK3R3) is comprised of a catalytic subunit and a regulatory subunit. The human p55 protein is composed of a rare amino terminal region followed by a proline-rich motif and two Src homology 2 (SH2) domains. PI 3-kinase p55 mRNAs are expressed in most human fetal and adult tissues, predominant expression is observed in the adult testis. Splice variant(s) of PI 3-kinase p55 have been identified, one of which has a deletion of 36 amino acids at the amino terminus and another which has an insertion of 59 amino acids at position 256 between the SH2 domains. Research suggests that PI 3-kinase p55 interacts with the IGFIR (Insulin-like growth factor-I receptor) and IR (Insulin receptor) and may be involved in PI 3-kinase activation by these receptors. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA159945(PIK3R3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA159945(PIK3R3 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Gel: 10%SDS-PAGE, Lysate: 40 ?g, Lane 1-5: Mouse brain tissue, human fetal brain tissue, mouse testis tissue, hela cells, human fetal kidney tissue, Primary antibody: CSB-PA159945(PIK3R3 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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Наименование: PIK3R3 Antibody.