| Объем | 50 мкг |
| Синонимы | Ras-related protein Rab-7b, RAB7B |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q96AH8 |
| Иммуноген | Recombinant Human Ras-related protein Rab-7b protein (100-199AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA |
| Примечание | Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Biotin |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Ras-related protein Rab-7b |
| Области исследований | Tags & Cell Markers, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
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Наименование: RAB7B Antibody, Biotin conjugated.