Phospho-NR3C1 (Ser226) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | GCCR, GCR, GRL, NR3C1, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P04150 | | Иммуноген | Peptide sequence around phosphorylation site of serine 226 (L-L-S(p)-P-L) derived from Human GR. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | <p>Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. Plays a significant role in transactivation.<br/><br/>Wehmeyer L, Du Toit A, Lang DM, Hapgood JP (2014) J Biol Chem 289, 10235-51 <br />Bouazza B, et al. (2014) Am J Respir Cell Mol Biol 50, 301-15 <br />Lee MS, et al. (2013) Behav Brain Res 236, 56-61 <br /></p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | | Абревеатура | Phospho-Ser226 | | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Jurkat cells treated with EGF using Phospho-GR (Ser226) antibody.The lane on the right is treated with the antigen-specific peptide.
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Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкл | | Кат. номер: | CSB-PA298129 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Phospho-NR3C1 (Ser226) Antibody.
Примечание: дополнительная информация (на английском языке). |
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