Объем | 100 мкл |
Синонимы | Presequence protease, mitochondrial (hPreP) (EC 3.4.24.-) (Pitrilysin metalloproteinase 1) (Metalloprotease 1) (hMP1), PITRM1, KIAA1104 MP1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q5JRX3 |
Иммуноген | Recombinant Human Presequence protease, mitochondrial protein (758-1037AA) |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
Примечание | ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity Purified |
Абревеатура | Presequence protease, mitochondrial |
Области исследований | Cell biology |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: PITRM1 antibody at 2.42µg/ml
Lane 1: Mouse placenta tissue
Lane 2: A549 whole cell lysate
Lane 3: Rat gonad tissue
Lane 4: Mouse kidney tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 118, 107 kDa
Observed band size: 118, 50 kDa
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Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA692283ESR2HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA692283ESR2HU at dilution of 1:100
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