RAF1 (Ab-259) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | C-RAF, C-Raf, CRAF | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P04049 | | Иммуноген | Peptide sequence around aa.257~261 (S-T-S-T-P) derived from Human RAF. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:200 | | Примечание | Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3.<br/><br/>Dougherty M K, et al. (2005) Mol Cell. 17(2): 215-224.<br/>Hekman M, et al. (2005) FEBS Lett. 579(2): 464-468.<br/>Avruch J,et al. (1994) Trends Biochem. Sci. 19, 279-283.<br/>Chong H, et al. (2001) EMBO J. 20, 3716-3727.<br/>King A J, et al. (1998) Nature. 396:180-183.<br/>Fabian J R, et al. (1993) Mol Cell Biol. 13: 7170-7179.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Cancer,Cell biology,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Hela, K562 and HT29 cells using Raf1(Ab-259) Antibody.
 | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Raf1(Ab-259) Antibody.
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Наименование: RAF1 (Ab-259) Antibody.