| Объем | 100 мкл |
| Синонимы | C-erbB-2, ErbB2, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P04626 |
| Иммуноген | Peptide sequence around phosphorylation site of tyrosine1248 (P-E-Y(p)-L-G) derived from Human HER2. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC, IF,WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200 |
| Примечание | <p>Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-a and amphiregulin. <br /><br />Yuan,Lu Qian ,Ming Shi, et al. (2008) HER2-dependent MMP-7 expression is mediated by activated STAT3 Guogang Cellular Signalling, 20:1284</p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Tyr1248 |
| Области исследований | Cancer,Tags & Cell Markers,Immunology,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells treated with PMA and MCF cells treated with EGF, using HER2 (Phospho-Tyr1248) Antibody.
 |
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HER2 (Phospho-Tyr1248) Antibody (left) or the same antibody preincubated with blocking peptide (right).
 |
Immunofluorescence staining of methanol-fixed MCF7 cells using HER2(Phospho-Tyr1248) Antibody.
 |
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue, using HER2 (Phospho-Tyr1248) Antibody.
 |
| | |
Наименование: Phospho-ERBB2 (Tyr1248) Antibody.