| Объем | 100 мкл |
| Синонимы | Growth factor receptor bound protein 2-associated protein 1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q13480 |
| Иммуноген | Peptide sequence around phosphorylation site of tyrosine 627 (V-E-Y(p)-L-D) derived from Human Gab1. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IF,WB:1:500-1:1000, IF:1:100-1:200 |
| Примечание | The protein encoded by Gab1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.<br/><br/>Anders Kallin, et al. (2004) J. Biol. Chem , 279: 17897 - 17904.<br/>Hideto Kameda, et al. (2001) Cell Growth Differ , 12: 307. <br/>Masaki Osawa, et al. (2002) J. Cell Biol , 158: 773.<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Tyr627 |
| Области исследований | Cancer,Cell biology,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells untreated or treated with EGF using Gab1(Phospho-Tyr627) Antibody.
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Immunofluorescence staining of methanol-fixed Hela cells using Gab1(Phospho-Tyr627) Antibody.
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Наименование: Phospho-GAB1 (Tyr627) Antibody.