Объем | 100 мкл |
Синонимы | CX43, CXA1, CXN-43, GJA1, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P17302 |
Иммуноген | Peptide sequence around phosphorylation site of serine 368(R-A-S(p)-S-R) derived from Human Connexin 43. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 |
Примечание | <p>One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. <br /><br />Joell L. Solan1, et al. (2003) Cell Science 116: 2203-2211 <br />Satoshi Matsushita, et al. (2006) Histochemistry and Cytochemistry 54 (3): 343-353, <br />Xiaoyong Bao, et al. (2004) Cell Physiol 286: C647-C654 <br />W. E. I. Li, et al.(1998) European Journal of Neuroscience 10: 2444 <br /> ,</p> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Абревеатура | Phospho-Ser368 |
Области исследований | Cardiovascular,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells untreated or treated with PMA using Connexin 43(phospho-Ser368) Antibody.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Connexin 43(Phospho-Ser367) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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