Объем | 100 мкл |
Синонимы | HMG box containing protein 1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O60381 |
Иммуноген | Peptide sequence around phosphorylation site of serine 402 (C-G-S(p)-P-G) derived from Human HBP1. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Абревеатура | Phospho-Ser402 |
Области исследований | Epigenetics and Nuclear Signaling,Cardiovascular,Stem cells |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from A549 cells, treated with PMA (125ng/ml, 30mins), using HBP1 (Phospho-Ser402) antibody. The lane on the right is treated with the synthesized peptide.
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