RARB AntibodyСпецификация| Объем | 100 мкл | | Синонимы | RAR-beta, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P10826 | | Иммуноген | Synthesized peptide derived from human Retinoic Acid Receptor beta. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.<br/><br/>Reuben Lotan, N. Engl. J. Med., May 1995, 332: 1405 - 1411. <br/>Andrew Yen, Mol. Pharmacol., Dec 2004, 66: 1727 - 1737. <br/>K Swisshelm, Cell Growth Differ., Feb 1994, 5: 133. <br/>F Aoudjit, Cell Growth Differ., May 1995, 6: 515. <br/><br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Retinoic Acid Receptor ? antibody.
 | Western blot analysis of extracts from HepG2 cells, using Retinoic Acid Receptor ? antibody.
 | Western blot analysis of extracts from K562 cells (Lane 2), using Retinoic Acid Receptor ? antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: RARB Antibody.