| Объем | 100 мкл |
| Синонимы | KS6A1, KS6AA, MAPKAP-K1a, RSK1, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q15418/P51812/Q15349/Q9UK32 |
| Иммуноген | Peptide sequence around phosphorylation site of Serine 221/227/218/232(A-Y-S(p)-F-C) derived from Human RSK1/2/3/4. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:1000 |
| Примечание | <p>This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. <br/><br/>Moller D.E., Am. J. Physiol. 266:C351-C359(1994).<br />Gregory S.G., Nature 441:315-321(2006).<br />The MGC Project Team, Genome Res. 14:2121-2127(2004).</p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Ser221/227/S218/232 |
| Области исследований | Epigenetics and Nuclear Signaling,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells (Lane 2), using RSK1/2/3/4 (Phospho-Ser221/227/218/232) Antibody. The lane on the left is treated with antigen-specific peptide.
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Наименование: Phospho-RPS6KA1/RPS6KA3/RPS6KA2/RPS6KA6 (Ser221/227/S218/232) Antibody.