| Объем | 100 мкл |
| Синонимы | JV15-2, MAD-3, MADH3, Smad 3, Mothers against decapentaplegic homolog 3 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P84022 |
| Иммуноген | Peptide sequence around phosphorylation site of serine213(P-M-S(p)-P-A) derived from Human Smad3 . |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB,WB:1:500-1:1000 |
| Примечание | <p>Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. <br/><br/>Zelivianski S, Cooley A, Kall R, Jeruss JS (2010) Mol Cancer Res 8, 1375-87. Alarc篓鐣 |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Ser213 |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Metabolism,Signal transduction,Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HT29 tissue using Smad3 (Phospho-Ser213) antibody.The lane on the right is treated with the antigen-specific peptide.
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Наименование: Phospho-SMAD3 (Ser213) Antibody.