Объем | 100 мкл |
Синонимы | HSF 1, HSTF1, Heat shock factor protein 1, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q00613 |
Иммуноген | Peptide sequence around phosphorylation site of threonine 142(L-L-T(p)-D-V) derived from Human HSF1 . |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, IHC,IHC:1:50-1:100 |
Примечание | <p>DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. <br/><br/>Rabindran S.K., Proc. Natl. Acad. Sci. U.S.A. 88:6906-6910(1991).<br />The MGC Project Team, Genome Res. 14:2121-2127(2004).<br />Schuetz T.J.,Proc. Natl. Acad. Sci. U.S.A. 88:6911-6915(1991)<br /></p> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Абревеатура | Phospho-Thr142 |
Области исследований | Epigenetics and Nuclear Signaling,Cardiovascular,Tags & Cell Markers |
Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemical analysis of paraffin-embedded human brain tissue using HSF1 (Phospho-Thr142) antibody (left)or the same antibody preincubated with blocking peptide (right).
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