Объем | 100 мкл |
Синонимы | OXSR1, kinase OSR1, Oxidative-stress responsive 1, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O95747 |
Иммуноген | Peptide sequence around phosphorylation site of threonine185(R-K-T(p)-F-V) derived from Human OSR1. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 |
Примечание | <p>Oxidative-stress responsive 1 gene is located in the vicinity of three others genes - GOLGA4, ITGA9 and HYA22 on chromosome 3. These four genes are considered to be candidate tumor suppressors. Oxidative-stress responsive 1 protein has similarity to human Ste20/oxidant stress response kinase-1 and is thought to be involved in the response to oxidative stress<br/><br/>Tamari M., J. Hum. Genet. 44:116-120(1999).<br />Kikuno R., DNA Res. 6-197-205(1999).<br />The MGC Project Team, Genome Res. 14:2121-2127(2004).</p> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Абревеатура | Phospho-Thr185 |
Области исследований | Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells treated with serum using OSR1 (Phospho-Thr185) Antibody.The lane on the right is treated with the antigen-specific peptide.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using OSR1 (Phospho-Thr185) antibody (left)or the same antibody preincubated with blocking peptide (right).
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