| Объем | 100 мкл |
| Синонимы | PLD 1, hPLD1, Choline phosphatase 1, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q13393 |
| Иммуноген | Peptide sequence around phosphorylation site of threonine 147(R-H-T(p)-F-R) derived from Human PLD1. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB,WB:1:500-1:1000 |
| Примечание | <p>Phosphatidylcholine (PC)-specific phospholipases D (PLDs, EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis.<br/><br/>Hammond S.M., J. Biol. Chem. 272:3860-3868(1997) [PubMed: 9013646].<br />Steed P.M., FASEB J. 12:1309-1317(1998) [PubMed: 9761774].<br />Lopez I., J. Biol. Chem. 273:12846-12852(1998) [PubMed: 9582313].<br /></p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Thr147 |
| Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells using PLD1 (Phospho-Thr147) Antibody.The lane on the right is treated with the antigen-specific peptide.
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Наименование: Phospho-PLD1 (Thr147) Antibody.