POLB AntibodyСпецификация| Объем | 100 мкл | | Синонимы | DNA polymerase beta, EC 2.7.7.7, EC 4.2.99, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P06746 | | Иммуноген | Synthesized peptide derived from human DNA Polymerase beta. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<br/><br/>Hiroyuki Matsumoto, Plant Cell Physiol., Nov 1981, 22: 1317 - 1324.<br/>L.K. Karagyozov, Nucleic Acids Res., Jun 1978, 5: 1907 - 1917.<br/>F Costanzo, J. Virol., Mar 1977, 21: 996 - 1001.<br/>AJ Faber, Eur. J. Biochem., Nov 1981, 120: 357.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from NIH/3T3 cells, using DNA Polymerase ? antibody.
 | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using DNA Polymerase ? antibody.
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Наименование: POLB Antibody.