PIAS3 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | PROTEIN INHIBITOR OF ACTIVATED STAT3, protein inhibitor of activated STAT 3, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9Y6X2 | | Иммуноген | Synthesized peptide derived from Internal of human PIAS3. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth.<br/><br/>Jiang-Hong Man, Nucleic Acids Res., Nov 2006, 34: 5552 - 5566. <br/>Amir Sonnenblick, Mol. Cell. Biol., Dec 2004, 24: 10584 - 10592. <br/>Jianyin Long, PNAS, Jan 2004, 101: 99. <br/>Hyun Duk Jang, J. Biol. Chem., Jun 2004, 279: 24873 - 24880.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling,Cell biology | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from 293 cells, treated with UV (5mins), using PIAS3 antibody.
 | Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using PIAS3 antibody.
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Наименование: PIAS3 Antibody.