PIKFYVE AntibodyСпецификацияОбъем | 100 мкл | Синонимы | 1-phosphatidylinositol-4-phosphate 5-kinase, EC 2.7.1.68, FYV1, FYVE finger-containing phosphoinositide kinase, KIAA0981 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q9Y2I7 | Иммуноген | Synthesized peptide derived from internal of human PIP5K. | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 | Примечание | The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/ multivesicular bodies (MVB) transport intermediates from early endosomes.<br/><br/>Ota T., Nat. Genet. 36:40-45(2004).<br/>Sbrissa D., J. Biol. Chem. 277:6073-6079(2002).<br/>Brill L.M., Anal. Chem. 76:2763-2772(2004).<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Cancer,Metabolism,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HepG2 cells, using PIP5K antibody.
| Immunofluorescence analysis of COS7 cells, using PIP5K antibody.
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