Объем | 100 мкл |
Синонимы | STMN1, STN1, stathmin |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P16949 |
Иммуноген | Peptide sequence around phosphorylation site of serine 38 (P-L-S(p)-P-P) derived from Human Stathmin 1. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 |
Примечание | Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear <br/><br/>Wang KK, et al. (1991) Biochem J 279(Pt 2): 537-544.<br/>Sekimoto T, et al. (2004) EMBO J 23(9): 1934-1942.<br/>Doye V, et al. (1992) Biochem J 287(Pt 2): 549-554.<br/>Larsson N, et al. (1999) Mol Cell Biol 19(3): 2242-2250.<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Абревеатура | Phospho-Ser38 |
Области исследований | Neuroscience,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from K562 cells untreated or treated with starvation using Stathmin 1(Phospho-Ser38) Antibody.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Stathmin 1(Phospho-Ser38) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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