Phospho-TH (Ser40) AntibodyСпецификацияОбъем | 100 мкл | Синонимы | TY3H, TYH, Tyrosine 3-hydroxylase, tyrosine hydroxylase, | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P07101 | Иммуноген | Peptide sequence around phosphorylation site of serine 40 (R-Q-S(p)-L-I) derived from Human Tyrosine Hydroxylase (TH). | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, IF,IF:1:100-1:200 | Примечание | The protein encoded by Tyrosine Hydroxylase is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.<br/><br/>Vazin T, et al. Stem Cells. 2008 Jun,26(6):1517-25<br/>Pistocchi A, et al. BMC Dev Biol. 2008 Mar 10,8:27 <br/>Fukakusa A, et al. J Pharmacol Sci. 2008 Feb,106(2):321-4.<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | Абревеатура | Phospho-Ser40 | Области исследований | Neuroscience,Cancer,Metabolism | Ссылка на страницу на сайте производителя | ссылка | Immunofluorescence staining of methanol-fixed Hela cells using Tyrosine Hydroxylase(Phospho-Ser40) Antibody.
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