PICK1 Antibody, Biotin conjugated

Спецификация

Объем	100 мкг
Синонимы	PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein), PICK1, PRKCABP
Клональность	Polyclonal Antibody
Организм	Human
uniprot	Q9NRD5
Иммуноген	Recombinant Human PRKCA-binding protein (1-200AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex, the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Biotin
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Области исследований	Neuroscience, Signal transduction
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкг
	Кат. номер:	CSB-PA05445D0Rb
Цена (с НДС 20%):	по запросу	В корзину
Наименование: PICK1 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке).