PPP1R12A AntibodyСпецификацияОбъем | 100 мкл | Синонимы | protein phosphatase 1, regulatory subunit 12A | Клональность | Polyclonal Antibody | Организм | Human | uniprot | O14974 | Иммуноген | Fusion protein of human PPP1R12A | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,ELISA:1:1000-1:2000, WB:1:200-1:1000 | Примечание | Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Epigenetics and Nuclear Signaling,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Gel: 6%SDS-PAGE, Lysate: 40 ?g, Lane: A172 cells, Primary antibody: CSB-PA300875(PPP1R12A Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
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