| Объем | 100 мкг |
| Синонимы | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PP2A subunit B isoform B55-delta) (PP2A subunit B isoform PR55-delta) (PP2A subunit B isoform R2-delta) (PP2A subunit B isoform delta), PPP2R2D, KIAA1541 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q66LE6 |
| Иммуноген | Recombinant Human Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform protein (1-192AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, IF, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Примечание | B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform |
| Области исследований | Cell biology, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA727750LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human glioma using CSB-PA727750LA01HU at dilution of 1:100
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Immunofluorescent analysis of Hela cells using CSB-PA727750LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Western Blot
Positive WB detected in: U87 whole cell lysate, PC-3 whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate
All lanes: PPP2R2D antibody at 3.3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 53 kDa
Observed band size: 53 kDa
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Наименование: PPP2R2D Antibody.