RIN1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Ras and Rab interactor 1, Ras inhibitor JC99, Ras interaction/interference protein 1, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q13671 | | Иммуноген | Synthesized peptide derived from internal of human RIN1. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.<br/><br/>Colicelli J., Proc. Natl. Acad. Sci. U.S.A. 88:2913-2917(1991).<br/>Han L., Mol. Cell. Biol. 15:1318-1323(1995).<br/>Han L., Proc. Natl. Acad. Sci. U.S.A. 94:4954-4959(1997)<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Cancer,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from K562 cells, using RIN1 antibody.
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Наименование: RIN1 Antibody.