PLCG2 (Ab-1217) AntibodyСпецификацияОбъем | 100 мкл | Синонимы | PLC-IV, PLC-gamma2, Phospholipase C-gamma-2 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P16885 | Иммуноген | Peptide sequence around aa.1215~1219 (F-L-Y-D-T) derived from Human PLCg2. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, IHC, IF,IHC:1:50-1:100, IF:1:100-1:200 | Примечание | The production of the second messenger molecules diacylglycerol. (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.<br/><br/>Singer, W. D. et al. (1997) Annu. Rev. Biochem. 66, 475-509.<br/>Smrcka, A. V. et al. (1991) Science 251, 804-807.<br/>Yue, C. et al. (2000) J. Biol. Chem. 275, 30220-30225.<br/>Watanabe, D. et al. (2001) J. Biol. Chem. 276, 38595-38601.<br/><br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using PLC-g2(Ab-1217) Antibody(left) or the same antibody preincubated with blocking peptide(right).
| Immunofluorescence staining of methanol-fixed Hela cells using PLC-g2(Ab-1217) Antibody.
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