PRKAB2 AntibodyСпецификация| Объем | 50 мкл | | Синонимы | 5'-AMP-activated protein kinase subunit beta-2 (AMPK subunit beta-2), PRKAB2 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | O43741 | | Иммуноген | Recombinant Human 5'-AMP-activated protein kinase subunit beta-2 protein (1-272AA) | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, Recommended dilution: WB:1:500-1:2000 | | Примечание | Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen Affinity Purified | | Области исследований | Cancer, Cardiovascular, Metabolism, Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot
All lanes: PRKAB2 antibody at 5µg/ml
Lane 1: Rat brain tissue
Lane 2: Mouse heart tissue
Lane 3: Mouse gonad tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 31, 22 kDa
Observed band size: 31 kDa
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Наименование: PRKAB2 Antibody.