PKM AntibodyСпецификацияОбъем | 100 мкл | Синонимы | pyruvate kinase, muscle | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P14618 | Иммуноген | Fusion protein of human PKM | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,ELISA:1:500-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 | Примечание | This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Metabolism,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA999488(PKM Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ?200)
| Gel: 8%SDS-PAGE, Lysate: 30 ?g, Lane: Hela cells, Primary antibody: CSB-PA999488(PKM Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
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