Объем | 50 мкг |
Синонимы | Phorbol-12-myristate-13-acetate-induced protein 1 (PMA-induced protein 1) (Immediate-early-response protein APR) (Protein Noxa), PMAIP1, NOXA |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q13794 |
Иммуноген | Recombinant Human Phorbol-12-myristate-13-acetate-induced protein 1 protein (1-136AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA |
Примечание | Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Biotin |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Phorbol-12-myristate-13-acetate-induced protein 1 |
Области исследований | Cancer, Cell biology, Metabolism |
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