| Объем | 50 мкл |
| Синонимы | prepronociceptin |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q13519 |
| Иммуноген | Synthetic peptide of human PNOC |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, IHC,ELISA:1:2000-1:5000, IHC:1:50-1:200 |
| Примечание | Nociception, a pain response mechanism, occurs in response to stimuli that threaten the integrity of an organism. The first synapses produced as a result of the initiation of nociception are modulated by excitatory amino acids (glutamate and aspartate) and many peptides (substance P, CGRP, CCK, endogenous opioids). Nociceptin (also designated orphanin FQ) is a neuronal peptide that is similar to opioid peptides. Nociceptin activates KOR-3 (kappa-type opioid receptor, also designated ORL1), a G protein-coupled receptor. Although similar to dynorphin A, a kappa opioid peptide, nociceptin functions to make animals hyperreactive to nociceptive stimulations. Nociceptin is also involved in locomotor behavior and may be involved in the modulation of synaptic plasticity in learning and memory. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Neuroscience |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA090243(PNOC Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA090243(PNOC Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Наименование: PNOC Antibody.