PODXL Antibody, HRP conjugated

Спецификация

Объем	50 мкг
Синонимы	Podocalyxin (GCTM-2 antigen) (Gp200) (Podocalyxin-like protein 1) (PC) (PCLP-1), PODXL, PCLP PCLP1
Клональность	Polyclonal Antibody
Организм	Human
uniprot	O00592
Иммуноген	Recombinant Human Podocalyxin protein (32-458AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin-dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up inital epithelial polarization and the apical lumen formation during renal tubulogenesis. Plays a role in cancer development and aggressiveness by inducing cell migration and invasion through its interaction with the actin-binding protein EZR. Affects EZR-dependent signaling events, leading to increased activities of the MAPK and PI3K pathways in cancer cells.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	HRP
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Области исследований	Cancer, Cardiovascular, Signal transduction, Stem cells
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	50 мкг
	Кат. номер:	CSB-PA13447B0Rb
Цена (с НДС 20%):	по запросу	В корзину
Наименование: PODXL Antibody, HRP conjugated. Примечание: дополнительная информация (на английском языке).