RRM1 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Ribonucleotide reductase M1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P23921 | Иммуноген | Fusion protein of human RRM1 | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, WB,ELISA:1:2000-1:5000, WB:1:500-1:2000 | Примечание | This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Epigenetics and Nuclear Signaling | Ссылка на страницу на сайте производителя | ссылка | Gel: 10%SDS-PAGE, Lysate: 50 ?g, Lane: Hela cells, Primary antibody: CSB-PA236550(RRM1 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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