POU2F1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | NF-A1, OCT1, OTF-1, Octamer-binding transcription factor 1, PO21 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P14859 | | Иммуноген | Synthesized peptide derived from human OCT-1. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | <p>Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR By similarity. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.<br /><br />Rikke H. Lewinsky, Hum. Mol. Genet., Dec 2005, 14: 3945 - 3953. <br />Harikrishna Nakshatri, J. Biol. Chem., Aug 1995, 270: 19613. <br />Mingfeng Liu, Eur. J. Biochem., May 2003, 270: 2274. <br />Vivek Mittal, Genes &, Dev., Jul 1999, 13: 1807. </p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human lymph node tissue using OCT-1 antibody.
 | Western blot analysis of extracts from HeLa cells, using OCT-1 antibody.
 | Western blot analysis of extracts from A549 cells (Lane 2), using OCT1 antiobdy. The lane on the left is treated with systhesized peptide.
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Наименование: POU2F1 Antibody.