| Объем | 100 мкл |
| Синонимы | 1-Oct, OTF1, oct-1B |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P14859 |
| Иммуноген | Peptide sequence around aa.270~274(T-P-K-R-I) derived from Human Oct-1. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IF,WB:1:500-1:1000, IF:1:100-1:200 |
| Примечание | <p>Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR By similarity. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes. <br /><br />Prefontaine G.G., Walther R., Giffin W. J. Biol. Chem. 274:26713-26719(1999) <br />Mahajan S.S., Wilson A.C. Mol. Cell. Biol. 20:919-928(2000)</p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from JK, HepG2 and 293 cells using Oct-1 Antibody.
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Immunofluorescence staining of methanol-fixed NCI-h446 cells showing cytoplasmic staining using Oct-1 Antibody.
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Наименование: POU2F1 Antibody.