| Объем | 50 мкл |
| Синонимы | Protein phosphatase 1A (EC 3.1.3.16) (Protein phosphatase 2C isoform alpha) (PP2C-alpha) (Protein phosphatase IA), PPM1A, PPPM1A |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P35813 |
| Иммуноген | Recombinant Human Protein phosphatase 1A protein (1-382AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
| Примечание | Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Абревеатура | Protein phosphatase 1A |
| Области исследований | Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: PPM1A antibody at 6.88µg/ml
Lane 1: HepG2 whole cell lysate
Lane 2: SH-SY5Y whole cell lysate
Lane 3: Mouse liver tissue
Lane 4: Mouse brain tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 43, 36, 52 kDa
Observed band size: 43 kDa
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Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA018489DSR1HU at dilution of 1:100
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Наименование: PPM1A Antibody.