S100A1 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | S100-ALPHA , S100 CALCIUM-BINDING PROTEIN A1, | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P23297 | Иммуноген | Synthesized peptide derived from human S100 A1. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 | Примечание | Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.<br/><br/>Patrick Most, J. Biol. Chem., Nov 2003, 278: 48404 - 48412. <br/>Miki Okada, J. Biol. Chem., Feb 2004, 279: 4221 - 4233. <br/>Melanie Boerries, Mol. Cell. Biol., Jun 2007, 27: 4365 - 4373. <br/>Patrick Most, J. Clin. Invest., Dec 2004, 114: 1550 - 1563. <br/><br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Epigenetics and Nuclear Signaling,Cell biology | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human brain tissue using S100 A1 antibody.
| Immunofluorescence analysis of A549 cells, using S100 A1 antibody.
| Western blot analysis of extracts from A549 cells, using S100 A1 antibody.
| Western blot analysis of extracts from 293 cells (Lane 2), using S100 A1 antiobdy. The lane on the left is treated with synthesized peptide.
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