RAD50 AntibodyСпецификация| Объем | 50 мкл | | Синонимы | RAD50 homolog (S. cerevisiae) | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q92878 | | Иммуноген | Synthetic peptide of human RAD50 | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:50-1:200 | | Примечание | The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Epigenetics and Nuclear Signaling | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA075718(RAD50 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ?200)
 | The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA075718(RAD50 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ?200)
 | Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane 1-5: 293T cells, Hela cells, K562 cells, NIH/3T3 cells, RAW264.7 cells, Primary antibody: CSB-PA075718(RAD50 Antibody) at dilution 1/900, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
 | | | |
Информация для заказа |
Наименование: RAD50 Antibody.