SDHB AntibodyСпецификация| Объем | 50 мкл | | Синонимы | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P21912 | | Иммуноген | Synthetic peptide of human SDHB | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 | | Примечание | Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Cancer,Cell biology,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA992496(SDHB Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ?200)
 | Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane 1-5: 293T cells, mouse brain tissue, human fetal liver tissue, hepg2 cells, Jurkat cells, Primary antibody: CSB-PA992496(SDHB Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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Наименование: SDHB Antibody.