PSME4 Antibody, Biotin conjugated

Спецификация

Объем	50 мкг
Синонимы	Proteasome activator complex subunit 4 (Proteasome activator PA200), PSME4, KIAA0077
Клональность	Polyclonal Antibody
Организм	Human
uniprot	Q14997
Иммуноген	Recombinant Human Proteasome activator complex subunit 4 protein (105-198AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during spermatogenesis and DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. Component of the spermatoproteasome, a form of the proteasome specifically found in testis: binds to acetylated histones and promotes degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. Also involved in DNA damage response in somatic cells, by promoting degradation of histones following DNA double-strand breaks.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Biotin
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	Proteasome activator complex subunit 4
Области исследований	Cell biology
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	50 мкг
	Кат. номер:	CSB-PA618917LD01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: PSME4 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке).