PRKAB1 Monoclonal AntibodyСпецификация| Объем | 100 мкл | | Синонимы | 1300015D22Rik, 5 AMP activated protein kinase subunit beta 1, 5-AMP-activated protein kinase subunit beta-1, AAKB1_HUMAN, AMP-ACTIVATED PROTEIN KINASE, NONCATALYTIC, BETA-1, AMP-activated, noncatalytic, beta-1, AMPK, AMPK beta 1 chain, | | Видовая специфичность | Human | | Uniport ID | Q9Y478 | | Иммуноген | Purified recombinant human AMPK beta 1 protein fragments expressed in E.coli. | | Источник | Mouse | | Видовая специфичность 1 | Human,Mouse,Rat,Monkey | | Применение | ELISA,WB,IHC,ICC,IP,Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500,ICC:1:50-1:200,IP:1:200-1:2000 | | Примечание | Non-catalytic subunit of AMP-activated protein kinase (AMPK),an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism.In response to reduction of intracellular ATP levels,AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein,carbohydrate and lipid biosynthesis,as well as cell growth and proliferation.AMPK acts via direct phosphorylation of metabolic enzymes,and by longer-term effects via phosphorylation of transcription regulators.Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton,probably by indirectly activating myosin.Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles,via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1,PRKAG2 or PRKAG3). | | Изотип | IgG | | Метод очистки | Affinity purified | | Коньюгат | Non-conjugated | | Буффер | Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction | | Станица на сайте производителя | ссылка | | | |
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Наименование: PRKAB1 Monoclonal Antibody.