PRKACB AntibodyСпецификация| Объем | 50 мкг | | Синонимы | cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11), PRKACB | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P22694 | | Иммуноген | Recombinant Human cAMP-dependent protein kinase catalytic subunit beta protein (2-53AA) | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC, IF, Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 | | Примечание | Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Абревеатура | cAMP-dependent protein kinase catalytic subunit beta | | Области исследований | Cancer, Metabolism, Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western Blot
Positive WB detected in: A549 whole cell lysate, MCF-7 whole cell lysate, PC-3 whole cell lysate, Rat brain tissue, Mouse brain tissue
All lanes: PRKACB antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 41, 47, 40, 42, 30, 37 kDa
Observed band size: 41, 47 kDa
 | Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA018689LA01HU at dilution of 1:100
 | Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA018689LA01HU at dilution of 1:100
 | Immunofluorescent analysis of Hela cells using CSB-PA018689LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Наименование: PRKACB Antibody.