Объем | 100 мкл |
Синонимы | Meiotic recombination protein REC8 homolog, Cohesin Rec8p, REC8, REC8L1, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O95072 |
Иммуноген | Synthesized peptide derived from internal of human REC8. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II By similarity.<br/><br/>Parisi S., Mol. Cell. Biol. 19:3515-3528(1999).<br/>Ota T., Nat. Genet. 36:40-45(2004).<br/>Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling,Cell biology |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from K562 cells, using REC8 antibody.
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