PTRH2 AntibodyСпецификацияОбъем | 50 мкл | Синонимы | peptidyl-tRNA hydrolase 2 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q9Y3E5 | Иммуноген | Fusion protein of human PTRH2 | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, WB, IHC,ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:10-1:50 | Примечание | PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1 (Bcl-2 inhibitor of transcription 1), is a 179 amino acid mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondia to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. It is also believed that the natural substrate for PTRH2 may be petidyl-tRNAs, which leave the ribosomes during protein synthesis. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology,Metabolism | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA846950(PTRH2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ?200)
| Gel: 12%SDS-PAGE, Lysate: 40 ?g, Lane 1-5: Raji cells, Jurkat cells, 231 cells, hepg2 cells, K562 cells, Primary antibody: CSB-PA846950(PTRH2 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
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