SETD7 Antibody, Biotin conjugated

Спецификация

Объем	100 мкг
Синонимы	Histone-lysine N-methyltransferase SETD7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase SETD7) (H3-K4-HMTase SETD7) (Lysine N-methyltransferase 7) (SET domain-containing protein 7) (SET7/9), SETD7, KIAA1717 KMT7 SET7 SET9
Клональность	Polyclonal Antibody
Организм	Human
uniprot	Q8WTS6
Иммуноген	Recombinant Human Histone-lysine N-methyltransferase SETD7 protein (1-366AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Biotin
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	Histone-lysine N-methyltransferase SETD7
Области исследований	Epigenetics and Nuclear Signaling
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкг
	Кат. номер:	CSB-PA840975LD01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: SETD7 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке).