SIX1 Antibody, HRP conjugated

Спецификация

Объем	50 мкг
Синонимы	Homeobox protein SIX1 (Sine oculis homeobox homolog 1), SIX1
Клональность	Polyclonal Antibody
Организм	Human
uniprot	Q15475
Иммуноген	Recombinant Human Homeobox protein SIX1 protein (144-262AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development. Plays an important role in the development of several organs, including kidney, muscle and inner ear. Depending on context, functions as transcriptional repressor or activator. Lacks an activation domain, and requires interaction with EYA family members for transcription activation. Mediates nuclear translocation of EYA1 and EYA2. Binds the 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the MYOG promoter. Regulates the expression of numerous genes, including MYC, CCND1 and EZR. Acts as activator of the IGFBP5 promoter, probably coactivated by EYA2. Repression of precursor cell proliferation in myoblasts is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex. During myogenesis, seems to act together with EYA2 and DACH2 (By similarity). Regulates the expression of CCNA1.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	HRP
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	Homeobox protein SIX1
Области исследований	Epigenetics and Nuclear Signaling, Cancer
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	50 мкг
	Кат. номер:	CSB-PA618986LB01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: SIX1 Antibody, HRP conjugated. Примечание: дополнительная информация (на английском языке).