RNF4 Antibody, FITC conjugatedСпецификацияОбъем | 50 мкг | Синонимы | E3 ubiquitin-protein ligase RNF4 (EC 2.3.2.27) (RING finger protein 4) (RING-type E3 ubiquitin transferase RNF4) (Small nuclear ring finger protein) (Protein SNURF), RNF4, SNURF | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P78317 | Иммуноген | Recombinant Human E3 ubiquitin-protein ligase RNF4 protein (1-103AA) | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA | Примечание | E3 ubiquitin-protein ligase which binds polysumoylated chains covalently attached to proteins and mediates 'Lys-6'-, 'Lys-11'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination of those substrates and their subsequent targeting to the proteasome for degradation. Regulates the degradation of several proteins including PML and the transcriptional activator PEA3. Involved in chromosome alignment and spindle assembly, it regulates the kinetochore CENPH-CENPI-CENPK complex by targeting polysumoylated CENPI to proteasomal degradation. Regulates the cellular responses to hypoxia and heat shock through degradation of respectively EPAS1 and PARP1. Alternatively, it may also bind DNA/nucleosomes and have a more direct role in the regulation of transcription for instance enhancing basal transcription and steroid receptor-mediated transcriptional activation. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | FITC | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | >95%, Protein G purified | Абревеатура | E3 ubiquitin-protein ligase RNF4 | Области исследований | Others | Ссылка на страницу на сайте производителя | ссылка | | |
Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | Антитела | Объем: | 50 мкг | Кат. номер: | CSB-PA019889LC01HU | Цена (с НДС 20%): | по запросу | В корзину | Наименование: RNF4 Antibody, FITC conjugated. Примечание: дополнительная информация (на английском языке). |
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