ROS1 AntibodyСпецификацияОбъем | 50 мкг | Синонимы | Protein ROS1 (EC 3.2.2.-) (DEMETER-like protein 1) (Repressor of silencing 1), ROS1, DML1 | Клональность | Polyclonal Antibody | Организм | Arabidopsis thaliana | uniprot | Q9SJQ6 | Иммуноген | Recombinant Arabidopsis thaliana Protein ROS1 protein (1-320AA) | Источник | Rabbit | Видовая специфичность | Arabidopsis thaliana | Применение | ELISA | Примечание | Bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity (PubMed:25240767). Generates 3'-phosphor-alpha,beta-unsaturated aldehyde (3'-PUA) as a primary 5-meC excision intermediate (PubMed:25228464). Prevents DNA hypermethylation, specifically in the promoter of otherwise silenced loci. May be involved in DNA repair through its nicking activity on methylated DNA. Binds with similar affinity to both methylated and non-methylated DNA. Highly distributive behavior on DNA substrates containing multiple 5-meC residues. Involved with Pol IV in the remodeling of the 5S rDNA chromatin via DNA methylation modifications during the first days of development post-germination. Participates in UV-B induced- and oxidative DNA damage repair (PubMed:24155752). | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | >95%, Protein G purified | Абревеатура | Protein ROS1 | Области исследований | Others | Ссылка на страницу на сайте производителя | ссылка | | |
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